IL 3 signaling pathway
| PAG Title | IL 3 signaling pathway |
| PAG ID | WIG000355 |
| Type | P |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding to its receptor. The receptor for IL-3 is a heterodimer with a ligand-specific alpha chain (70 kD, CD123) and a common beta chain (shared with IL-5 and GM-CSF). Signaling is believed to be primarily through Stat5 and the MAPK pathways. |
| Species | Homo sapiens |
| nCoCo Score | 3,373 |
| Base PAG ID | WIG000355 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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